5月10日，来自南卡罗来纳大学（University of South Carolina）的王倩教授来我院做题目为《Self-Assembly of Virus Nanoparticles for Materials Applications》学术报告。
The overall research objective of Dr. Wang’s group focuses on using chemical biology tools to probe intracellular activities and the development of hierarchically structured nanomaterials to study the cooperative response of cells to extracellular matrixes. Dr. Wang’s group works on using functional proteins and protein nanoparticles (like viruses) as building blocks for materials development and biomedical applications. The protein based nanoparticles can be readily obtained in large quantity and modified with chemical and genetic methods. In particular, compared with the synthetic macromolecules, the uniform shape and size of viral particles provide highly promising possibilities in self-assembly study for the construction of nanoscale materials with hierarchical ordering. On the basis of the surface modification with conventional bioconjugation chemistry, “click” reaction, and genetic modification, we can control the self-assembly of spherical particles and rod-like viruses with polymers to form 1D, 2D and 3D self-assemblies. These hierarchically assembled biomaterials offer a unique scaffold for vaccine delivery and tissue engineering applications.